Metabolome-wide association study of organophosphate pesticide exposure
نویسندگان
چکیده
منابع مشابه
Biological monitoring of genotoxicity to organophosphate pesticide exposure among rice farmers: Exposure-effect continuum study
Background: This study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (OP) toxicity and its genotoxic effect among rice farmers. Materials and Methods: A cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. They share the common socio-economical ...
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PURPOSE To determine if plasma metabolic profiles can detect differences between patients with neovascular age-related macular degeneration (NVAMD) and similarly-aged controls. METHODS Metabolomic analysis using liquid chromatography with Fourier-transform mass spectrometry (LC-FTMS) was performed on plasma samples from 26 NVAMD patients and 19 controls. Data were collected from mass/charge r...
متن کاملMetabolome-Wide Association Study of Primary Open Angle Glaucoma.
PURPOSE To determine if primary open-angle glaucoma (POAG) patients can be differentiated from controls based on metabolic characteristics. METHODS We used ultra-high resolution mass spectrometry with C18 liquid chromatography for metabolomic analysis on frozen plasma samples from 72 POAG patients and 72 controls. Metabolome-wide Spearman correlation was performed to select differentially exp...
متن کاملbiological monitoring of genotoxicity to organophosphate pesticide exposure among rice farmers: exposure-effect continuum study
background: this study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (op) toxicity and its genotoxic effect among rice farmers. materials and methods : a cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. they share the common socio-economica...
متن کاملAssociation of Organophosphate Pesticide Exposure and Paraoxonase with Birth Outcome in Mexican-American Women
BACKGROUND Epidemiologic studies suggest that maternal organophosphorus (OP) pesticide exposure is associated with poorer fetal growth, but findings are inconsistent. We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this association. METHODS The study population included 470 pregnant women enrolled in the CHAMACOS Study, a ...
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ژورنال
عنوان ژورنال: ISEE Conference Abstracts
سال: 2020
ISSN: 1078-0475
DOI: 10.1289/isee.2020.virtual.p-0803